ZBTB8OS Antibody, FITC conjugated

Code CSB-PA816894LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZBTB8OS Polyclonal antibody
Uniprot No.
Target Names
ZBTB8OS
Alternative Names
ARCH antibody; ARCH_HUMAN antibody; ARCH2 antibody; Archease (ARCH) antibody; Archease like protein antibody; MGC62007 antibody; OTTHUMP00000036124 antibody; Protein archease antibody; Protein ZBTB8OS antibody; ZBTB8OS antibody; Zinc finger and BTB domain containing 8 opposite strand antibody; Zinc finger and BTB domain containing opposite strand protein 8 antibody; Zinc finger and BTB domain-containing opposite strand protein 8 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein archease protein (2-136AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation.
Gene References into Functions
  1. ARCH mutation is associated with chronic myelomonocytic leukemia. PMID: 26648538
  2. RTCB, the catalytic subunit of the tRNA ligase complex, and its co-factor archease mediate XBP1 mRNA splicing both in vitro and in vivo. PMID: 25378478
  3. archease (also called ZBTB8OS), a protein of unknown function, is required for full activity of the human tRNA ligase complex and, in cooperation with DDX1, facilitates the formation of an RTCB-guanylate intermediate central to mammalian RNA ligation PMID: 24870230
Protein Families
Archease family
Database Links

HGNC: 24094

KEGG: hsa:339487

STRING: 9606.ENSP00000417677

UniGene: Hs.655921

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